ACTR1B (DGR32447) Rabbit mAb - diagbio | 戴格生物

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Recombinant DGRmAb^®

ACTR1B (DGR32447) Rabbit mAb

db14905

Datasheet

Product Name : ACTR1B (DGR32447) Rabbit mAb

Cat.No.: db14905

Synonyms : PC3; ARP1B; CTRN2

Application : WB, IHC-P, ICC/IF, FC, IP

Reactivity : Human

Host species : Rabbit

Background This gene encodes a 42.3 kD subunit of dynactin, a macromolecular complex consisting of 10 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein and is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, chromosome movement, nuclear positioning, and axonogenesis. This subunit, like ACTR1A, is an actin-related protein. These two proteins, which are of equal length and share 90% amino acid identity, are present in a constant ratio of approximately 1:15 in the dynactin complex. [provided by RefSeq, Aug 2008]
Immunogen A synthetic peptide of human ACTR1B
Gene ID 10120
Swiss Prot P42025
Synonyms PC3; ARP1B; CTRN2
Reactivity Human
Application WB, IHC-P, ICC/IF, FC, IP
Recommended dilution WB: 1:1000-1:5000
IHC-P: 1:100-1:200
ICC/IF: 1:100-1:200
FC: 1:200-1:500
IP: 1:100
Calculated MW 42 kDa
Observed MW 42 kDa
Host species Rabbit
Clonality Monoclonal
Clonality No. DGR32447
Isotype IgG
Purity Affinity Purification
Conjugation Un-conjugated
Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

Western blot detection of ACTR1B in Hela,A549,HL-60,U251,U87-MG cell lysates using ACTR1B antibody(1:1000 diluted).
Western blot analysis of extracts from HepG2 cells and Rat muscle， Mouse heart tissue using db14905 at 1:2000.
Immunohistochemical analysis of paraffin-embedded human breast cancer using db14905 antibody.
Immunofluorescent analysis of HeLa cells using db14905 antibody (green), and DAPI (blue).

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