Phospho-SIRT1 (Ser47) Rabbit pAb - diagbio | 戴格生物

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Phospho-SIRT1 (Ser47) Rabbit pAb

db1531

Product Name : Phospho-SIRT1 (Ser47) Rabbit pAb

Cat.No.: db1531

Synonyms : SIR2; SIR2L1; SIR2alpha

Application : WB, IHC, ICC/IF

Reactivity : Human

Host species : Rabbit

Background This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class I of the sirtuin family. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2008]
Immunogen A synthetic phosphopeptide corresponding to residues surrounding Ser47 of human SIRT1
Gene ID 23411
Swiss Prot Q96EB6
Synonyms SIR2; SIR2L1; SIR2alpha
Reactivity Human
Application WB, IHC, ICC/IF
Recommended dilution WB: 1:1000
IHC: 1:50
ICC/IF: 1:50
Calculated MW 82 kDa
Observed MW 120 kDa
Host species Rabbit
Clonality Polyclonal
Isotype IgG
Purity Affinity Purification
Conjugation Un-conjugated
Storage/Stability Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

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