MICA/MICB (DGR35332) Rabbit mAb - diagbio | 戴格生物

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Recombinant DGRmAb^®

MICA/MICB (DGR35332) Rabbit mAb

db16551

Datasheet

Product Name : MICA/MICB (DGR35332) Rabbit mAb

Cat.No.: db16551

Synonyms : MIC-A; PERB11.1; PERB11.2

Application : WB, FC, IP

Reactivity : Human

Host species : Rabbit

Background MICA and MICB proteins are stress - inducible molecules. They are expressed on the surface of cells under various stress conditions, such as infection, inflammation, or cellular transformation. Their main function is to serve as ligands for the NKG2D receptor, which is expressed on natural killer (NK) cells, cytotoxic T lymphocytes (CTLs), and some other immune cells. When MICA or MICB binds to NKG2D, it triggers an activating signal in the immune cells, leading to the activation of their cytotoxic functions. This helps the immune system to identify and eliminate stressed, infected, or transformed cells.
Immunogen Recombinant protein of human MICA/MICB
Gene ID 100507436
4277
Swiss Prot Q29980
Q29983
Synonyms MIC-A; PERB11.1; PERB11.2
Reactivity Human
Application WB, FC, IP
Recommended dilution WB: 1:1000
FC: 1:50
IP: 1:20-1:50
Calculated MW 43 kDa
Observed MW 50-75 kDa
Host species Rabbit
Clonality Monoclonal
Clonality No. DGR35332
Isotype IgG
Purity Affinity Purification
Conjugation Un-conjugated
Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

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