CCR3 (DGR35378) Rabbit mAb - diagbio | 戴格生物

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Recombinant DGRmAb^®

CCR3 (DGR35378) Rabbit mAb

db16555

Datasheet

Product Name : CCR3 (DGR35378) Rabbit mAb

Cat.No.: db16555

Synonyms : CKR3; CD193; CKR 3; CMKBR3; C C CKR3; CC-CKR-3

Application : WB, ICC/IF

Reactivity : Human

Host species : Rabbit

Background The protein encoded by this gene is a receptor for C-C type chemokines. It belongs to family 1 of the G protein-coupled receptors. This receptor binds and responds to a variety of chemokines, including eotaxin (CCL11), eotaxin-3 (CCL26), MCP-3 (CCL7), MCP-4 (CCL13), and RANTES (CCL5). It is highly expressed in eosinophils and basophils, and is also detected in TH1 and TH2 cells, as well as in airway epithelial cells. This receptor may contribute to the accumulation and activation of eosinophils and other inflammatory cells in the allergic airway. It is also known to be an entry co-receptor for HIV-1. This gene and seven other chemokine receptor genes form a chemokine receptor gene cluster on the chromosomal region 3p21. Alternatively spliced transcript variants have been described. [provided by RefSeq, Sep 2009]
Immunogen A synthetic peptide of human CCR3
Gene ID 1232
Swiss Prot P51677
Synonyms CKR3; CD193; CKR 3; CMKBR3; C C CKR3; CC-CKR-3
Reactivity Human
Application WB, ICC/IF
Recommended dilution WB: 1:1000
ICC/IF: 1:50
Calculated MW 41 kDa
Observed MW 45 kDa
Host species Rabbit
Clonality Monoclonal
Clonality No. DGR35378
Isotype IgG
Purity Affinity Purification
Conjugation Un-conjugated
Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

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