GLP1R (DGR35714) Rabbit mAb - diagbio | 戴格生物

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Recombinant DGRmAb^®

GLP1R (DGR35714) Rabbit mAb

db16576

Datasheet

Product Name : GLP1R (DGR35714) Rabbit mAb

Cat.No.: db16576

Synonyms : GLP-1; GLP-1R; GLP-1-R

Application : IHC-P

Reactivity : Human

Host species : Rabbit

Background This gene encodes a 7-transmembrane protein that functions as a receptor for glucagon-like peptide 1 (GLP-1) hormone, which stimulates glucose-induced insulin secretion. This receptor, which functions at the cell surface, becomes internalized in response to GLP-1 and GLP-1 analogs, and it plays an important role in the signaling cascades leading to insulin secretion. It also displays neuroprotective effects in animal models. Polymorphisms in this gene are associated with diabetes. The protein is an important drug target for the treatment of type 2 diabetes and stroke. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Apr 2016]
Immunogen Recombinant protein of human GLP1R
Gene ID 2740
Swiss Prot P43220
Synonyms GLP-1; GLP-1R; GLP-1-R
Reactivity Human
Application IHC-P
Recommended dilution IHC-P: 1:100
Calculated MW 53 kDa
Host species Rabbit
Clonality Monoclonal
Clonality No. DGR35714
Isotype IgG
Purity Affinity Purification
Conjugation Un-conjugated
Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

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