RNF20 Rabbit pAb - diagbio | 戴格生物

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RNF20 Rabbit pAb

db1873

Product Name : RNF20 Rabbit pAb

Cat.No.: db1873

Synonyms : BRE1; BRE1A; hBRE1

Application : WB, ICC/IF, FC, IP

Reactivity : Human, Mouse

Host species : Rabbit

Background The protein encoded by this gene shares similarity with BRE1 of S. cerevisiae. The protein encoded by this human gene is an E3 ubiquitin ligase that regulates chromosome structure by monoubiquitinating histone H2B. This protein acts as a putative tumor suppressor and positively regulates the p53 tumor suppressor as well as numerous histone H2A and H2B genes. In contrast, this protein also suppresses the expression of several protooncogenes and growth-related genes, including many genes that are induced by epidermal growth factor. This gene selectively suppresses the expression of some genes by interfering with chromatin recruitment of transcription elongation factor SII (TFIIS). [provided by RefSeq, Feb 2012]
Immunogen A synthetic peptide of human RNF20
Gene ID 56254
Swiss Prot Q5VTR2
Synonyms BRE1; BRE1A; hBRE1
Reactivity Human, Mouse
Application WB, ICC/IF, FC, IP
Recommended dilution WB: 1:1000
ICC/IF: 1:20-1:50
FC: 1:50
IP: 1:20
Calculated MW 114 kDa
Observed MW 120 kDa
Host species Rabbit
Clonality Polyclonal
Isotype IgG
Purity Affinity Purification
Conjugation Un-conjugated
Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

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