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Bcl-XL Rabbit pAb
db20843
Datasheet

Product Name : Bcl-XL Rabbit pAb

Cat.No.: db20843

Synonyms : BCLX; BCL2L; Bcl-X; PPP1R52; BCL-XL/S

Application : WB, IHC, IP

Reactivity : Human, Mouse, Rat

Host species : Rabbit

  • Background The protein encoded by this gene belongs to the BCL-2 protein family. BCL-2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. The proteins encoded by this gene are located at the outer mitochondrial membrane, and have been shown to regulate outer mitochondrial membrane channel (VDAC) opening. VDAC regulates mitochondrial membrane potential, and thus controls the production of reactive oxygen species and release of cytochrome C by mitochondria, both of which are the potent inducers of cell apoptosis. Alternative splicing results in multiple transcript variants encoding two different isoforms. The longer isoform acts as an apoptotic inhibitor and the shorter isoform acts as an apoptotic activator. [provided by RefSeq, Dec 2015]
  • Immunogen Recombinant protein of human Bcl-XL
  • Gene ID 598
  • Swiss Prot Q07817
  • Synonyms BCLX; BCL2L; Bcl-X; PPP1R52; BCL-XL/S
  • Reactivity Human, Mouse, Rat
  • Application WB, IHC, IP
  • Recommended dilution WB: 1:0000
    IHC: 1:1000
    IP: 1:50
  • Calculated MW 26 kDa
  • Observed MW 30 kDa
  • Host species Rabbit
  • Clonality Polyclonal
  • Isotype IgG
  • Purity Affinity Purification
  • Conjugation Un-conjugated
  • Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
订购信息
  • Package Price (RMB)
  • 20μL 598
  • 50μL 998
  • 100μL 1798
  • 货期:现货
For research use only. Not intended for diagnostic.