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PEN2 Rabbit pAb
db21233
Datasheet

Product Name : PEN2 Rabbit pAb

Cat.No.: db21233

Synonyms : PEN2; PEN-2; MDS033; ACNINV2; MSTP064

Application : WB, IHC, ICC/IF, FC

Reactivity : Human, Mouse, Rat

Host species : Rabbit

  • Background Presenilins, which are components of the gamma-secretase protein complex, are required for intramembranous processing of some type I transmembrane proteins, such as the Notch proteins and the beta-amyloid precursor protein. Signaling by Notch receptors mediates a wide range of developmental cell fates. Processing of the beta-amyloid precursor protein generates neurotoxic amyloid beta peptides, the major component of senile plaques associated with Alzheimer's disease. This gene encodes a protein that is required for Notch pathway signaling, and for the activity and accumulation of gamma-secretase. Mutations resulting in haploinsufficiency for this gene cause familial acne inversa-2 (ACNINV2). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]
  • Immunogen A synthetic peptide of human PEN2
  • Gene ID 55851
  • Swiss Prot Q9NZ42
  • Synonyms PEN2; PEN-2; MDS033; ACNINV2; MSTP064
  • Reactivity Human, Mouse, Rat
  • Application WB, IHC, ICC/IF, FC
  • Recommended dilution WB: 1:1000
    IHC: 1:50
    ICC/IF: 1:50
    FC: 1:20-1:100
  • Calculated MW 12 kDa
  • Observed MW 12 kDa
  • Host species Rabbit
  • Clonality Polyclonal
  • Isotype IgG
  • Purity Affinity Purification
  • Conjugation Un-conjugated
  • Storage/Stability Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
订购信息
  • Package Price (RMB)
  • 20μL 598
  • 50μL 998
  • 100μL 1798
  • 货期:现货
For research use only. Not intended for diagnostic.