IL-13 Rabbit pAb - diagbio | 戴格生物

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IL-13 Rabbit pAb

db21517

Product Name : IL-13 Rabbit pAb

Cat.No.: db21517

Synonyms : P600; IL-13

Application : WB

Reactivity : Human, Mouse, Rat

Host species : Rabbit

Background This gene encodes an immunoregulatory cytokine produced primarily by activated Th2 cells. This cytokine is involved in several stages of B-cell maturation and differentiation. It up-regulates CD23 and MHC class II expression, and promotes IgE isotype switching of B cells. This cytokine down-regulates macrophage activity, thereby inhibits the production of pro-inflammatory cytokines and chemokines. This cytokine is found to be critical to the pathogenesis of allergen-induced asthma but operates through mechanisms independent of IgE and eosinophils. This gene, IL3, IL5, IL4, and CSF2 form a cytokine gene cluster on chromosome 5q, with this gene particularly close to IL4. [provided by RefSeq, Jul 2008]
Immunogen A synthetic peptide of human IL-13
Gene ID 3596
Swiss Prot P35225
Synonyms P600; IL-13
Reactivity Human, Mouse, Rat
Application WB
Recommended dilution WB: 1:1000
Calculated MW 16 kDa
Observed MW 12 kDa
Host species Rabbit
Clonality Polyclonal
Isotype IgG
Purity Affinity Purification
Conjugation Un-conjugated
Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

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