Phospho-FANCD2 (Ser1404) Rabbit pAb
Product Name :
Phospho-FANCD2 (Ser1404) Rabbit pAb
Cat.No.:
db21963
Synonyms :
FA4; FAD; FACD; FAD2; FA-D2; FANCD
Application :
WB, ICC/IF
Reactivity :
Human, Mouse
Host species :
Rabbit
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Background
The Fanconi anemia complementation group (FANC) currently includes FANCA, FANCB, FANCC, FANCD1 (also called BRCA2), FANCD2, FANCE, FANCF, FANCG, FANCI, FANCJ (also called BRIP1), FANCL, FANCM and FANCN (also called PALB2). The previously defined group FANCH is the same as FANCA. Fanconi anemia is a genetically heterogeneous recessive disorder characterized by cytogenetic instability, hypersensitivity to DNA crosslinking agents, increased chromosomal breakage, and defective DNA repair. The members of the Fanconi anemia complementation group do not share sequence similarity; they are related by their assembly into a common nuclear protein complex. This gene encodes the protein for complementation group D2. This protein is monoubiquinated in response to DNA damage, resulting in its localization to nuclear foci with other proteins (BRCA1 AND BRCA2) involved in homology-directed DNA repair. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2016]
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Immunogen
A synthetic phosphopeptide corresponding to residues surrounding Ser1404 of human FANCD2
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Gene ID
2177
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Swiss Prot
Q9BXW9
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Synonyms
FA4; FAD; FACD; FAD2; FA-D2; FANCD
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Reactivity
Human, Mouse
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Application
WB, ICC/IF
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Recommended dilution
WB: 1:1000
ICC/IF: 1:50
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Calculated MW
55 kDa
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Observed MW
55 kDa
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Host species
Rabbit
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Clonality
Polyclonal
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Isotype
IgG
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Purity
Affinity Purification
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Conjugation
Un-conjugated
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Storage/Stability
Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
订购信息
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Package
Price (RMB)
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20μL
698
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50μL
1398
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100μL
2398
- 货期：现货
For research use only. Not intended for diagnostic.
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