Hsp70 Rabbit pAb - diagbio | 戴格生物

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Hsp70 Rabbit pAb

db2396

Product Name : Hsp70 Rabbit pAb

Cat.No.: db2396

Synonyms : Hsp70; hsp68; Hsp70-1; Hsp70.1

Application : WB, IHC, ICC/IF, FC

Reactivity : Human, Mouse, Rat

Host species : Rabbit

Background Molecular chaperone implicated in a wide variety of cellular processes, including protection of the proteome from stress, folding and transport of newly synthesized polypeptides, activation of proteolysis of misfolded proteins and the formation and dissociation of protein complexes. Plays a pivotal role in the protein quality control system, ensuring the correct folding of proteins, the re-folding of misfolded proteins and controlling the targeting of proteins for subsequent degradation. This is achieved through cycles of ATP binding, ATP hydrolysis and ADP release, mediated by co-chaperones. The co-chaperones have been shown to not only regulate different steps of the ATPase cycle, but they also have an individual specificity such that one co-chaperone may promote folding of a substrate while another may promote degradation. The affinity for polypeptides is regulated by its nucleotide bound state.
Immunogen Recombinant protein of mouse Hsp70
Gene ID 15511
Swiss Prot P17879
Synonyms Hsp70; hsp68; Hsp70-1; Hsp70.1
Reactivity Human, Mouse, Rat
Application WB, IHC, ICC/IF, FC
Recommended dilution WB: 1:1000
IHC: 1:1000
ICC/IF: 1:50
FC: 1:200
Calculated MW 70 kDa
Observed MW 70 kDa
Host species Rabbit
Clonality Polyclonal
Isotype IgG
Purity Affinity Purification
Conjugation Un-conjugated
Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

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