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JNK1/JNK2/JNK3 Rabbit pAb

Product Name : JNK1/JNK2/JNK3 Rabbit pAb

Cat.No.: db2618

Synonyms : JNK; JNK1; PRKM8; SAPK1; JNK-46; JNK1A2; SAPK1c; JNK21B1/2

Application : WB, ICC/IF, FC, IP

Reactivity : Human, Mouse, Rat

Host species : Rabbit

  • Background The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various cell stimuli, and targets specific transcription factors, and thus mediates immediate-early gene expression in response to cell stimuli. The activation of this kinase by tumor-necrosis factor alpha (TNF-alpha) is found to be required for TNF-alpha induced apoptosis. This kinase is also involved in UV radiation induced apoptosis, which is thought to be related to cytochrom c-mediated cell death pathway. Studies of the mouse counterpart of this gene suggested that this kinase play a key role in T cell proliferation, apoptosis and differentiation. Several alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Apr 2016]
  • Immunogen Recombinant protein of human JNK1
  • Gene ID 5599
  • Swiss Prot P45983
  • Synonyms JNK; JNK1; PRKM8; SAPK1; JNK-46; JNK1A2; SAPK1c; JNK21B1/2
  • Reactivity Human, Mouse, Rat
  • Application WB, ICC/IF, FC, IP
  • Recommended dilution WB: 1:1000
    ICC/IF: 1:200
    FC: 1:20
    IP: 1:20
  • Calculated MW 48,53 kDa
  • Observed MW 46,54 kDa
  • Host species Rabbit
  • Clonality Polyclonal
  • Isotype IgG
  • Purity Affinity Purification
  • Conjugation Un-conjugated
  • Storage/Stability Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
订购信息
  • Package Price (RMB)
  • 20μL 598
  • 50μL 998
  • 100μL 1798
  • 货期:现货
For research use only. Not intended for diagnostic.