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PMS2 (BP6116) Rabbit mAb
db30099
Datasheet

Product Name : PMS2 (BP6116) Rabbit mAb

Cat.No.: db30099

Synonyms : MLH4; PMSL2; HNPCC4; PMS2CL

Application : IHC

Reactivity : Human

Host species : Rabbit

  • Background The PMS2 protein forms a heterodimer with the MLH1 protein which is then activated in the presence of ATP; this complex coordinates the binding of other proteins that repair DNA errors arising during cell preparation for cell division. The loss of PMS2 expression in tumors can be helpful in identifying hMLH1 mutation carriers and identifies their suitability for mutation analysis.
  • Immunogen Synthetic peptide corresponding to residues within aa1-100 of PMS2 was used as an immunogen
  • Swiss Prot P54278
  • Synonyms MLH4; PMSL2; HNPCC4; PMS2CL
  • Reactivity Human
  • Application IHC
  • Recommended dilution IHC: 1:100-1:200
  • Calculated MW 96 kDa
  • Host species Rabbit
  • Clonality Monoclonal
  • Clonality No. BP6116
  • Isotype IgG
  • Purity Affinity Purification
  • Conjugation Un-conjugated
  • Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
  • Immunohistochemistry of paraffin-embedded human colon using PMS2 antibody at dilution of 1:200 (200x lens).
订购信息
  • Package Price (RMB)
  • 100μL 4140
  • 货期:现货
For research use only. Not intended for diagnostic.