Product Name :
PMS2 (BP6116) Rabbit mAb
Cat.No.:
db30099
Synonyms :
MLH4; PMSL2; HNPCC4; PMS2CL
Application :
IHC
Reactivity :
Human
Host species :
Rabbit
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Background
The PMS2 protein forms a heterodimer with the MLH1 protein which is then activated in the presence of ATP; this complex coordinates the binding of other proteins that repair DNA errors arising during cell preparation for cell division. The loss of PMS2 expression in tumors can be helpful in identifying hMLH1 mutation carriers and identifies their suitability for mutation analysis.
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Immunogen
Synthetic peptide corresponding to residues within aa1-100 of PMS2 was used as an immunogen
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Swiss Prot
P54278
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Synonyms
MLH4; PMSL2; HNPCC4; PMS2CL
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Reactivity
Human
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Application
IHC
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Recommended dilution
IHC: 1:100-1:200
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Calculated MW
96 kDa
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Host species
Rabbit
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Clonality
Monoclonal
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Clonality No.
BP6116
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Isotype
IgG
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Purity
Affinity Purification
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Conjugation
Un-conjugated
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Storage/Stability
Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
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Immunohistochemistry of paraffin-embedded human colon using PMS2 antibody at dilution of 1:200 (200x lens).
订购信息
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Package
Price (RMB)
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100μL
4140
- 货期:现货
For research use only. Not intended for diagnostic.