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SDHB (BP6160) Rabbit mAb
db30140
Datasheet
- Background Succinate dehydrogenase B (SDHB) is an iron-sulfur subunit of mitochondrial complex II, a key component of the citric acid cycle and the electron transport chain, a respiratory complex that catalyzes the oxidation of succinate in the mitochondrial membrane. Many cancers are generally positive for SDHB, including renal cell carcinomas and gastrointestinal stromal tumors. A subset of RCC and GIST tumors that are associated with SDH mutations, Carney-Stratakis Syndrome or Carney Triad exhibit a loss of SDHB expression.
- Immunogen Synthetic peptide corresponding to residues in Human SDHB was used as an immunogen
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Swiss Prot
P21912
- Synonyms IP; SDH; CWS2; PGL4; SDH1; SDH2; SDHIP
- Reactivity Human
- Application IHC
- Recommended dilution IHC: 1:100-1:200
- Calculated MW 32 kDa
- Host species Rabbit
- Clonality Monoclonal
- Clonality No. BP6160
- Isotype IgG
- Purity Affinity Purification
- Conjugation Un-conjugated
- Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
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Immunohistochemistry of paraffin-embedded human kidney using SDHB antibody at dilution of 1:200 (200x lens).
订购信息
- Package Price (RMB)
- 100μL 5292
- 货期：现货
相关产品
For research use only. Not intended for diagnostic.
