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CD146 Recombinant Rabbit mAb
db30142
Datasheet
- Background CD146 plays a role in cell adhesion, and in cohesion of the endothelial monolayer at intercellular junctions in vascular tissue. Its expression may allow melanoma cells to interact with cellular elements of the vascular system, thereby enhancing hematogeneous tumor spread. Could be an adhesion molecule active in neural crest cells during embryonic development. Acts as surface receptor that triggers tyrosine phosphorylation of FYN and PTK2/FAK1, and a transient increase in the intracellular calcium concentration.
- Immunogen Full length rprotein (purified) corresponding to Human Human CD146
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Swiss Prot
P43121
- Synonyms CD146; MUC18
- Reactivity Human
- Application IHC
- Recommended dilution IHC: 1:100-1:200
- Calculated MW 72 kDa
- Host species Rabbit
- Clonality Monoclonal
- Clonality No. BP6162
- Isotype IgG
- Purity Affinity Purification
- Conjugation Un-conjugated
- Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
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Immunohistochemistry of paraffin-embedded human placenta using CD146 antibody at dilution of 1:200 (200x lens).
订购信息
- Package Price (RMB)
- 100μL 1798
- 货期：现货
相关产品
For research use only. Not intended for diagnostic.
