Oct3/4 Recombinant Rabbit mAb - diagbio | 戴格生物

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Oct3/4 Recombinant Rabbit mAb

db30144

Product Name : Oct3/4 Recombinant Rabbit mAb

Cat.No.: db30144

Synonyms : OCT3; OCT4; OTF3; OTF4; OTF-3; Oct-3; Oct-4

Application : IHC

Reactivity : Human

Host species : Rabbit

Background OCT-4, also known as OTF3 or POU5F1, is a member of the POU family of transcription factors, involved in the regulation of pluripotency during normal development and is detectable in embryonic stem and germ cells. It can specifically bind to the octamer motif (5'-ATTTCAT-3'), and it is critical for the self-renewal of embryonic stem cells. OCT-4 is a key regulator of self?renewal in embryonic stem cells; its expression is potentially correlated with tumorigenesis and can affect some aspects of tumor behavior such as tumor recurrence or resistance to therapies. OCT-4 is a sensitive and specific marker for germ cell tumors.
Immunogen Synthetic peptide corresponding to residues in Human Oct-3/4 was used as an immunogen
Swiss Prot Q01860
Synonyms OCT3; OCT4; OTF3; OTF4; OTF-3; Oct-3; Oct-4
Reactivity Human
Application IHC
Recommended dilution IHC: 1:100-1:200
Calculated MW 38.5 kDa
Host species Rabbit
Clonality Monoclonal
Clonality No. BP6164
Isotype IgG
Purity Affinity Purification
Conjugation Un-conjugated
Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

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