c-Myc Recombinant Rabbit mAb - diagbio | 戴格生物

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c-Myc Recombinant Rabbit mAb

db30161

Product Name : c-Myc Recombinant Rabbit mAb

Cat.No.: db30161

Synonyms : MRTL; MYCC; c-Myc; bHLHe39

Application : IHC

Reactivity : Human

Host species : Rabbit

Background Oncogene-encoded proteins c-Myc, n-Myc, and l-Myc function in cell proliferation, differentation and neoplastic disease. A mutated version of Myc is found in many cancers, which causes Myc to be constitutively expressed. This leads to the unregulated expression of many genes, some of which are involved in cell proliferation, and result in the formation of cancer. c-Myc is a transcription factor and is a proto-oncogene that is the focal point in cell cycle regulation, metabolism, apoptosis, differentiation, cell adhesion, and tumorigenesis.
Immunogen Synthetic peptide residues in human c-Myc was used as an immunogen
Swiss Prot P01106
Synonyms MRTL; MYCC; c-Myc; bHLHe39
Reactivity Human
Application IHC
Recommended dilution IHC: 1:100-1:200
Calculated MW 48 kDa
Host species Rabbit
Clonality Monoclonal
Clonality No. BP6195
Isotype IgG
Purity Affinity Purification
Conjugation Un-conjugated
Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

Immunohistochemistry of paraffin-embedded human tonsil using c-Myc antibody at dilution of 1:200 (200x lens).

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