BRG1 Recombinant Rabbit mAb - diagbio | 戴格生物

产品中心 Products Center

您当前的位置：

BRG1 Recombinant Rabbit mAb

db30165

Product Name : BRG1 Recombinant Rabbit mAb

Cat.No.: db30165

Synonyms : BRG1; CSS4; SNF2; SWI2; MRD16; RTPS2; BAF190; SNF2L4; SNF2LB; hSNF2b; BAF190A

Application : IHC

Reactivity : Human

Host species : Rabbit

Background Transcriptional coactivator cooperating with nuclear hormone receptors to potentiate transcriptional activation. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex.
Immunogen Full length protein corresponding to Human BRG1
Swiss Prot P51532
Synonyms BRG1; CSS4; SNF2; SWI2; MRD16; RTPS2; BAF190; SNF2L4; SNF2LB; hSNF2b; BAF190A
Reactivity Human
Application IHC
Recommended dilution IHC: 1:100-1:200
Calculated MW 185 kDa
Host species Rabbit
Clonality Monoclonal
Clonality No. BP6201
Isotype IgG
Purity Affinity Purification
Conjugation Un-conjugated
Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

Immunohistochemistry of paraffin-embedded human kidney using BRG1 antibody at dilution of 1:200 (200x lens).

订购信息