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MDM2 (BP6203) Rabbit mAb
db30167
Datasheet
- Background The MDM2 (murine double minute-2) protein was initially identified as an oncogene in a murine transformation system. MDM2 functions to bind p53 and block p53-mediated transactivation of cotransfected reporter constructs. p53 is the most commonly mutated gene in human cancer identified to date. Expression of p53 leads to inhibition of cell growth by preventing progression of cells from G1 to S phase of the cell cycle.
- Immunogen Synthetic peptide within Human MDM2
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Swiss Prot
Q00987
- Synonyms HDMX; hdm2; ACTFS
- Reactivity Human
- Application IHC, WB
- Recommended dilution IHC: 1:100-1:200
- Calculated MW 55 kDa
- Host species Rabbit
- Clonality Monoclonal
- Clonality No. BP6203
- Isotype IgG
- Purity Affinity Purification
- Conjugation Un-conjugated
- Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
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Immunohistochemistry of paraffin-embedded human dedifferentiated liposarcoma using MDM2 antibody at dilution of 1:200 (200x lens).
订购信息
- Package Price (RMB)
- 100μL 3960
- 货期：现货
相关产品
For research use only. Not intended for diagnostic.
