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MGMT (BP6217) Rabbit mAb
db30177
Datasheet
- Background Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
- Immunogen A synthetic peptide corresponding to residues on the N-terminus of human MGMT was used as an immunogen
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Swiss Prot
P16455
- Synonyms 6-O-methylguanine-DNA methyltransferase; O-6-methylguanine-DNA-alkyltransferase
- Reactivity Human
- Application IHC, WB
- Recommended dilution IHC: 1:100-1:200
- Calculated MW 22 kDa
- Host species Rabbit
- Clonality Monoclonal
- Clonality No. BP6217
- Isotype IgG
- Purity Affinity Purification
- Conjugation Un-conjugated
- Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
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Immunohistochemistry of paraffin-embedded human appendix using MGMT antibody at dilution of 1:200 (200x lens).
订购信息
- Package Price (RMB)
- 100μL 2340
- 货期：现货
相关产品
For research use only. Not intended for diagnostic.
