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GATA-3 (BP6229) Rabbit mAb
db30187
Datasheet
- Background GATA binding protein 3 or GATA-3, is a zinc finger transcription factor and plays an important role in promoting and directing cell proliferation, development, and differentiation in many tissues and cell types. GATA-3 is one of the three genes mutated in 10% of breast cancers. Nuclear expression of GATA-3 in breast cancer is considered a marker of luminal cancer in ER+ cancer and luminal androgen responsive cancer in ER-/AR+ tumors. It is highly coexpressed with FOXA1 and serves as negative predictor of basal subtype and HER-2 and is also considered a strong predictor of taxane and platin salts insensitivity.
- Immunogen Synthetic peptide. This information is proprietary to Biolynx
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Swiss Prot
P23771
- Synonyms HDR; HDRS
- Reactivity Human
- Application IHC, WB
- Recommended dilution IHC: 1:100-1:200
- Calculated MW 48 kDa
- Host species Rabbit
- Clonality Monoclonal
- Clonality No. BP6229
- Isotype IgG
- Purity Affinity Purification
- Conjugation Un-conjugated
- Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
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Immunohistochemistry of paraffin-embedded human breast cancer using GATA-3 antibody at dilution of 1:200 (200x lens).
订购信息
- Package Price (RMB)
- 100μL 1980
- 货期：现货
相关产品
For research use only. Not intended for diagnostic.
