p16 Recombinant Mouse mAb - diagbio | 戴格生物

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p16 Recombinant Mouse mAb

db30195

Product Name : p16 Recombinant Mouse mAb

Cat.No.: db30195

Synonyms : ARF; MLM; P14; P16; P19; CMM2; INK4; MTS1; TP16; CDK4I; CDKN2; INK4A; MTS-1; P14ARF; P19ARF; P16INK4; P16INK4A; P16-INK4A

Application : IHC

Reactivity : Human

Host species : Mouse

Background The progression of cells through the cell cycle is regulated by a family of protein kinases known as cyclin-dependent kinases (Cdks). The sequential activation of individual members of this family and their consequent phosphorylation of critical substrates promotes orderly progression through the cell cycle. Moreover, the gene encoding p16 INK4A exhibits a high frequency of homozygous deletions and point mutations in established human tumor cell lines.
Immunogen Full length recombinant p16 INK4A of human origin was used as an immunogen
Swiss Prot P42771
Synonyms ARF; MLM; P14; P16; P19; CMM2; INK4; MTS1; TP16; CDK4I; CDKN2; INK4A; MTS-1; P14ARF; P19ARF; P16INK4; P16INK4A; P16-INK4A
Reactivity Human
Application IHC
Recommended dilution IHC: 1:100-1:200
Calculated MW 17 kDa
Host species Mouse
Clonality Monoclonal
Clonality No. BPM6238
Isotype IgG
Purity Affinity Purification
Conjugation Un-conjugated
Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

Immunohistochemistry of paraffin-embedded human cervical intraepithelial neoplasias using p16 antibody at dilution of 1:200 (200x lens).

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