PRAME Recombinant Rabbit mAb - diagbio | 戴格生物

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PRAME Recombinant Rabbit mAb

db30204

Product Name : PRAME Recombinant Rabbit mAb

Cat.No.: db30204

Synonyms : MAPE; OIP4; CT130; OIP-4

Application : IHC, WB

Reactivity : Human

Host species : Rabbit

Background PRAME (preferentially expressed antigen in melanoma) is a cancer/testis antigen not normally expressed in any tissues except testis, but is upregulated in tumors. PRAME is expressed in melanoma cells and is recognized by cytolytic T-cells. It is also upregulated in other diseases, such as synovial sarcoma, NSCLC, and breast cancer, where it is thought to contribute to tumorigenesis and metastasis. PRAME is also highly expressed in liquid tumors such as AML and can be predictive of clinical outcome in some circumstances.
Immunogen Recombinant protein fragment of human PRAME was used as an immunogen
Swiss Prot P78395
Synonyms MAPE; OIP4; CT130; OIP-4
Reactivity Human
Application IHC, WB
Recommended dilution IHC: 1:100-1:200
Calculated MW 58 kDa
Host species Rabbit
Clonality Monoclonal
Clonality No. BP6248
Isotype IgG
Purity Affinity Purification
Conjugation Un-conjugated
Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

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