Claudin18.2 Recombinant Rabbit mAb - diagbio | 戴格生物

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Claudin18.2 Recombinant Rabbit mAb

db30205

Product Name : Claudin18.2 Recombinant Rabbit mAb

Cat.No.: db30205

Application : IHC, WB

Reactivity : Human

Host species : Rabbit

Background Claudin18.2 (CLDN18.2) is a splice variant of the membrane epithelial tight junctions protein Claudin18 (CLDN18) and has been identified as a promising biomarker for targeted therapy. While upon malignant transformation, the changes in cell polarity lead to the exposure of CLDN18.2 epitopes. which are suitable for targeted therapy. Prior evidence demonstrates that except for GC, CLDN18.2 is aberrantly expressed in various primary tumors and metastases, including pancreatic, biliary, ovarian, and lung adenocarcinomas, which makes CLDN18.2 a pan-cancer target.
Immunogen Recombinant protein fragment of human Claudin18.2 was used as an immunogen
Swiss Prot P56856-2
Reactivity Human
Application IHC, WB
Recommended dilution IHC: 1:100-1:200
Calculated MW 28 kDa
Host species Rabbit
Clonality Monoclonal
Clonality No. BP6249
Isotype IgG
Purity Affinity Purification
Conjugation Un-conjugated
Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

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