CD68 Rabbit pAb - diagbio | 戴格生物

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CD68 Rabbit pAb

db3194

Product Name : CD68 Rabbit pAb

Cat.No.: db3194

Synonyms : GP110; LAMP4; SCARD1

Application : WB, IHC, ICC/IF

Reactivity : Human

Host species : Rabbit

Background This gene encodes a 110-kD transmembrane glycoprotein that is highly expressed by human monocytes and tissue macrophages. It is a member of the lysosomal/endosomal-associated membrane glycoprotein (LAMP) family. The protein primarily localizes to lysosomes and endosomes with a smaller fraction circulating to the cell surface. It is a type I integral membrane protein with a heavily glycosylated extracellular domain and binds to tissue- and organ-specific lectins or selectins. The protein is also a member of the scavenger receptor family. Scavenger receptors typically function to clear cellular debris, promote phagocytosis, and mediate the recruitment and activation of macrophages. Alternative splicing results in multiple transcripts encoding different isoforms. [provided by RefSeq, Jul 2008]
Immunogen A synthetic peptide of human CD68
Gene ID 968
Swiss Prot P34810
Synonyms GP110; LAMP4; SCARD1
Reactivity Human
Application WB, IHC, ICC/IF
Recommended dilution WB: 1:1000
IHC: 1:5000
ICC/IF: 1:100
Calculated MW 37 kDa
Observed MW 130-140 kDa
Host species Rabbit
Clonality Polyclonal
Isotype IgG
Purity Affinity Purification
Conjugation Un-conjugated
Storage/Stability Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

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