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Phospho-p53 (Ser392) Rabbit pAb

Product Name : Phospho-p53 (Ser392) Rabbit pAb

Cat.No.: db33

Synonyms : P53; BCC7; LFS1; TRP53

Application : WB, IHC, ICC/IF, IP

Reactivity : Human

Host species : Rabbit

  • Background This gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li-Fraumeni syndrome. Alternative splicing of this gene and the use of alternate promoters result in multiple transcript variants and isoforms. Additional isoforms have also been shown to result from the use of alternate translation initiation codons from identical transcript variants (PMIDs: 12032546, 20937277). [provided by RefSeq, Dec 2016]
  • Immunogen A synthetic phosphopeptide corresponding to residues surrounding Ser392 of human p53
  • Gene ID 7157
  • Swiss Prot P04637
  • Synonyms P53; BCC7; LFS1; TRP53
  • Reactivity Human
  • Application WB, IHC, ICC/IF, IP
  • Recommended dilution WB: 1:2000
    IHC: 1:50
    ICC/IF: 1:50
    IP: 1:20
  • Calculated MW 44 kDa
  • Observed MW 53 kDa
  • Host species Rabbit
  • Clonality Polyclonal
  • Isotype IgG
  • Purity Affinity Purification
  • Conjugation Un-conjugated
  • Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
订购信息
  • Package Price (RMB)
  • 20μL 698
  • 50μL 1398
  • 100μL 2398
  • 货期:现货
For research use only. Not intended for diagnostic.