NMDAR2A Rabbit pAb - diagbio | 戴格生物

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NMDAR2A Rabbit pAb

db339

Product Name : NMDAR2A Rabbit pAb

Cat.No.: db339

Synonyms : NR2A; GluN2A; NMDAR2A

Application : WB

Reactivity : Mouse, Rat

Host species : Rabbit

Background Component of NMDA receptor complexes that function as heterotetrameric, ligand-gated ion channels with high calcium permeability and voltage-dependent sensitivity to magnesium (PubMed:1374164). Channel activation requires binding of the neurotransmitter glutamate to the epsilon subunit, glycine binding to the zeta subunit, plus membrane depolarization to eliminate channel inhibition by Mg2+. Sensitivity to glutamate and channel kinetics depend on the subunit composition; channels containing GRIN1 and GRIN2A have higher sensitivity to glutamate and faster kinetics than channels formed by GRIN1 and GRIN2B (By similarity). Contributes to the slow phase of excitatory postsynaptic current, long-term synaptic potentiation, and learning (PubMed:7816096, PubMed:8987814).
Immunogen Recombinant protein of mouse NMDAR2A
Gene ID 14811
Swiss Prot P35436
Synonyms NR2A; GluN2A; NMDAR2A
Reactivity Mouse, Rat
Application WB
Recommended dilution WB: 1:1000
Calculated MW 165 kDa
Observed MW 165 kDa
Host species Rabbit
Clonality Polyclonal
Isotype IgG
Purity Affinity Purification
Conjugation Un-conjugated
Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

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