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ALIX Rabbit pAb

Product Name : ALIX Rabbit pAb

Cat.No.: db3753

Synonyms : AIP1; ALIX; HP95; DRIP4

Application : WB

Reactivity : Human

Host species : Rabbit

  • Background This gene encodes a protein that functions within the ESCRT pathway in the abscission stage of cytokinesis, in intralumenal endosomal vesicle formation, and in enveloped virus budding. Studies using mouse cells have shown that overexpression of this protein can block apoptosis. In addition, the product of this gene binds to the product of the PDCD6 gene, a protein required for apoptosis, in a calcium-dependent manner. This gene product also binds to endophilins, proteins that regulate membrane shape during endocytosis. Overexpression of this gene product and endophilins results in cytoplasmic vacuolization, which may be partly responsible for the protection against cell death. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene. Related pseudogenes have been identified on chromosome 15. [provided by RefSeq, Jan 2012]
  • Immunogen Recombinant protein of human ALIX
  • Gene ID 10015
  • Swiss Prot Q8WUM4
  • Synonyms AIP1; ALIX; HP95; DRIP4
  • Reactivity Human
  • Application WB
  • Recommended dilution WB: 1:1000-1:2000
  • Calculated MW 96 kDa
  • Observed MW 96 kDa
  • Host species Rabbit
  • Clonality Polyclonal
  • Isotype IgG
  • Purity Affinity Purification
  • Conjugation Un-conjugated
  • Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
订购信息
  • Package Price (RMB)
  • 20μL 598
  • 50μL 998
  • 100μL 1798
  • 货期:现货
For research use only. Not intended for diagnostic.