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5HT2C Receptor Rabbit pAb

Product Name : 5HT2C Receptor Rabbit pAb

Cat.No.: db4401

Synonyms : HTR1C; 5-HT1C; 5-HT2C; 5HTR2C; 5-HTR2C

Application : WB

Reactivity : Human, Mouse, Rat

Host species : Rabbit

  • Background This gene encodes a seven-transmembrane G-protein-coupled receptor. The encoded protein responds to signaling through the neurotransmitter serotonin. The mRNA of this gene is subject to multiple RNA editing events, where adenosine residues encoded by the genome are converted to inosines. RNA editing is predicted to alter the structure of the second intracellular loop, thereby generating alternate protein forms with decreased ability to interact with G proteins. Abnormalities in RNA editing of this gene have been detected in victims of suicide that suffer from depression. In addition, naturally-occuring variation in the promoter and 5' non-coding and coding regions of this gene may show statistically-significant association with mental illness and behavioral disorders. Alternative splicing results in multiple different transcript variants. [provided by RefSeq, Jan 2015]
  • Immunogen A synthetic peptide of human 5HT2C Receptor
  • Gene ID 3358
  • Swiss Prot P28335
  • Synonyms HTR1C; 5-HT1C; 5-HT2C; 5HTR2C; 5-HTR2C
  • Reactivity Human, Mouse, Rat
  • Application WB
  • Recommended dilution WB: 1:1000-1:5000
  • Calculated MW 52 kDa
  • Observed MW 52 kDa
  • Host species Rabbit
  • Clonality Polyclonal
  • Isotype IgG
  • Purity Affinity Purification
  • Conjugation Un-conjugated
  • Storage/Stability Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
订购信息
  • Package Price (RMB)
  • 20μL 598
  • 50μL 998
  • 100μL 1798
  • 货期:现货
For research use only. Not intended for diagnostic.