BACE1 Rabbit pAb - diagbio | 戴格生物

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BACE1 Rabbit pAb

db5038

Product Name : BACE1 Rabbit pAb

Cat.No.: db5038

Synonyms : ASP2; Bace; C76936

Application : WB, IHC, IP

Reactivity : Mouse, Rat

Host species : Rabbit

Background This gene encodes a member of the peptidase A1 family of aspartic proteases. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature protease. This transmembrane protease catalyzes the first step in the formation of amyloid beta peptide from amyloid precursor protein. Amyloid beta peptides are the main constituent of amyloid beta plaques, which accumulate in the brains of human Alzheimer's disease patients. Homozygous knockout mice for this gene exhibit a wide range of nervous system defects, growth retardation, metabolic abnormalities, and increased neonatal lethality. [provided by RefSeq, Nov 2015]
Immunogen Recombinant protein of mouse BACE1
Gene ID 23821
Swiss Prot P56818
Synonyms ASP2; Bace; C76936
Reactivity Mouse, Rat
Application WB, IHC, IP
Recommended dilution WB: 1:1000
IHC: 1:50
IP: 1:20
Calculated MW 56 kDa
Observed MW 70 kDa
Host species Rabbit
Clonality Polyclonal
Isotype IgG
Purity Affinity Purification
Conjugation Un-conjugated
Storage/Stability Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

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