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Myelin Basic Protein Rabbit pAb
db5475
Datasheet

Product Name : Myelin Basic Protein Rabbit pAb

Cat.No.: db5475

Synonyms : MBP; Myelin A1 protein; Myelin membrane encephalitogenic protein

Application : WB, IHC

Reactivity : Human, Mouse, Rat

Host species : Rabbit

  • Background The protein encoded by the classic MBP gene is a major constituent of the myelin sheath of oligodendrocytes and Schwann cells in the nervous system. However, MBP-related transcripts are also present in the bone marrow and the immune system. These mRNAs arise from the long MBP gene (otherwise called "Golli-MBP") that contains 3 additional exons located upstream of the classic MBP exons. Alternative splicing from the Golli and the MBP transcription start sites gives rise to 2 sets of MBP-related transcripts and gene products. The Golli mRNAs contain 3 exons unique to Golli-MBP, spliced in-frame to 1 or more MBP exons. They encode hybrid proteins that have N-terminal Golli aa sequence linked to MBP aa sequence. The second family of transcripts contain only MBP exons and produce the well characterized myelin basic proteins. This complex gene structure is conserved among species suggesting that the MBP transcription unit is an integral part of the Golli transcription unit and that this arrangement is important for the function and/or regulation of these genes. [provided by RefSeq, Jul 2008]
  • Immunogen A synthetic peptide of human Myelin Basic Protein
  • Gene ID 4155
  • Swiss Prot P02686
  • Synonyms MBP; Myelin A1 protein; Myelin membrane encephalitogenic protein
  • Reactivity Human, Mouse, Rat
  • Application WB, IHC
  • Recommended dilution WB: 1:1000
    IHC: 1:500
  • Calculated MW 33 kDa
  • Observed MW 18 kDa
  • Host species Rabbit
  • Clonality Polyclonal
  • Isotype IgG
  • Purity Affinity Purification
  • Conjugation Un-conjugated
  • Storage/Stability Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
订购信息
  • Package Price (RMB)
  • 20μL 598
  • 50μL 998
  • 100μL 1798
  • 货期：现货
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For research use only. Not intended for diagnostic.