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Phospho-FADD (Ser194) Rabbit pAb

Product Name : Phospho-FADD (Ser194) Rabbit pAb

Cat.No.: db5543

Synonyms : GIG3; MORT1

Application : WB, IP

Reactivity : Human

Host species : Rabbit

  • Background The protein encoded by this gene is an adaptor molecule that interacts with various cell surface receptors and mediates cell apoptotic signals. Through its C-terminal death domain, this protein can be recruited by TNFRSF6/Fas-receptor, tumor necrosis factor receptor, TNFRSF25, and TNFSF10/TRAIL-receptor, and thus it participates in the death signaling initiated by these receptors. Interaction of this protein with the receptors unmasks the N-terminal effector domain of this protein, which allows it to recruit caspase-8, and thereby activate the cysteine protease cascade. Knockout studies in mice also suggest the importance of this protein in early T cell development. [provided by RefSeq, Jul 2008]
  • Immunogen A synthetic phosphopeptide corresponding to residues surrounding Ser194 of human FADD
  • Gene ID 8772
  • Swiss Prot Q13158
  • Synonyms GIG3; MORT1
  • Reactivity Human
  • Application WB, IP
  • Recommended dilution WB: 1:1000
    IP: 1:20
  • Calculated MW 23 kDa
  • Observed MW 28 kDa
  • Host species Rabbit
  • Clonality Polyclonal
  • Isotype IgG
  • Purity Affinity Purification
  • Conjugation Un-conjugated
  • Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
订购信息
  • Package Price (RMB)
  • 20μL 698
  • 50μL 1398
  • 100μL 2398
  • 货期:现货
For research use only. Not intended for diagnostic.