CHD3 Rabbit pAb - diagbio | 戴格生物

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CHD3 Rabbit pAb

db5878

Product Name : CHD3 Rabbit pAb

Cat.No.: db5878

Synonyms : ZFH; Mi-2a; Mi2-ALPHA

Application : WB, IHC, ICC/IF, FC

Reactivity : Human, Mouse, Rat

Host species : Rabbit

Background This gene encodes a member of the CHD family of proteins which are characterized by the presence of chromo (chromatin organization modifier) domains and SNF2-related helicase/ATPase domains. This protein is one of the components of a histone deacetylase complex referred to as the Mi-2/NuRD complex which participates in the remodeling of chromatin by deacetylating histones. Chromatin remodeling is essential for many processes including transcription. Autoantibodies against this protein are found in a subset of patients with dermatomyositis. Three alternatively spliced transcripts encoding different isoforms have been described. [provided by RefSeq, Jul 2008]
Immunogen A synthetic peptide of human CHD3
Gene ID 1107
Swiss Prot Q12873
Synonyms ZFH; Mi-2a; Mi2-ALPHA
Reactivity Human, Mouse, Rat
Application WB, IHC, ICC/IF, FC
Recommended dilution WB: 1:1000
IHC: 1:20
ICC/IF: 1:20
FC: 1:20
Calculated MW 227 kDa
Observed MW 260 kDa
Host species Rabbit
Clonality Polyclonal
Isotype IgG
Purity Affinity Purification
Conjugation Un-conjugated
Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

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