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PRMT6 (2C3) Mouse mAb
db6024
Datasheet
- Background The protein encoded by this gene belongs to the arginine N-methyltransferase family, which catalyze the sequential transfer of methyl group from S-adenosyl-L-methionine to the side chain nitrogens of arginine residues within proteins, to form methylated arginine derivatives and S-adenosyl-L-homocysteine. This protein can catalyze both, the formation of omega-N monomethylarginine and asymmetrical dimethylarginine, with a strong preference for the latter. It specifically mediates the asymmetric dimethylation of Arg2 of histone H3, and the methylated form represents a specific tag for epigenetic transcriptional repression. This protein also forms a complex with, and methylates DNA polymerase beta, resulting in stimulation of polymerase activity by enhancing DNA binding and processivity.
- Immunogen Purified recombinant human PRMT6 protein fragments expressed in E.coli
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Gene ID
55170
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Swiss Prot
Q96LA8
- Synonyms HRMT1L6; PRMT 6
- Reactivity Human
- Application WB, IHC-F, IHC-P, ICC/IF
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Recommended dilution
WB: 1:500-1:1000
IHC: 1:50-1:100
ICC/IF: 1:50-1:200 - Calculated MW 42 kDa
- Observed MW 42 kDa
- Host species Mouse
- Clonality Monoclonal
- Clonality No. 2C3-F1-G1
- Isotype IgG1
- Purity Affinity Purification
- Conjugation Un-conjugated
- Storage/Stability Store at -20°C. Supplied in PBS, 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3. Stable for 12 months from date of receipt.
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Western blot analysis of PRMT6 in Hela and 293T lysates using PRMT6 antibody. -
Immunocytochemistry analysis of PRMT6 (2C3) in Hela using PRMT6 antibody. -
Immunohistochemistry analysis of paraffin-embedded Human breast cancer using PRMT6 antibody. High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval. -
Western blot analysis of PRMT6 in COS7, Jurkat and Hela lysates using PRMT6 antibody.
订购信息
- Package Price (RMB)
- 50μL 1398
- 100μL 2398
- 货期：现货
相关产品
For research use only. Not intended for diagnostic.
