p38 (5A1) Mouse mAb - diagbio | 戴格生物

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p38 (5A1) Mouse mAb

db6168

Product Name : p38 (5A1) Mouse mAb

Cat.No.: db6168

Synonyms : RK; p38; CSBP; EXIP; Mxi2; CSBP1; CSBP2; CSPB1; PRKM14; PRKM15; SAPK2A; p38ALPHA; MAPK14

Application : WB

Reactivity : Human, Mouse, Rat, Monkey

Host species : Mouse

Background Responds to activation by environmental stress, pro-inflammatory cytokines and lipopolysaccharide (LPS) by phosphorylating a number of transcription factors, such as ELK1 and ATF2 and several downstream kinases, such as MAPKAPK2 and MAPKAPK5. Plays a critical role in the production of some cytokines, for example IL-6. May play a role in stabilization of EPO mRNA during hypoxic stress. Isoform Mxi2 activation is stimulated by mitogens and oxidative stress and only poorly phosphorylates ELK1 and ATF2. Isoform Exip may play a role in the early onset of apoptosis.
Immunogen Purified recombinant human P38 MAPK Pprotein fragments expressed in E.coli
Gene ID 1432
Swiss Prot Q16539
Synonyms RK; p38; CSBP; EXIP; Mxi2; CSBP1; CSBP2; CSPB1; PRKM14; PRKM15; SAPK2A; p38ALPHA; MAPK14
Reactivity Human, Mouse, Rat, Monkey
Application WB
Recommended dilution WB: 1:500-1:1000
Calculated MW 41 kDa
Observed MW 41 kDa
Host species Mouse
Clonality Monoclonal
Clonality No. 5A1-C5-F11
Isotype IgG1
Purity Affinity Purification
Conjugation Un-conjugated
Storage/Stability Store at -20°C. Supplied in PBS, 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3. Stable for 12 months from date of receipt.

Western blot analysis of p38 (5A1) in C2C12, PC-12, HepG2, COS7, C6, 3T3 and Hela lysates using p38 MAPK antibody.

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