GADD45A (6C3) Mouse mAb - diagbio | 戴格生物

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GADD45A (6C3) Mouse mAb

db6240

Product Name : GADD45A (6C3) Mouse mAb

Cat.No.: db6240

Synonyms : DDIT1; GADD45

Application : WB

Reactivity : Transfected

Host species : Mouse

Background This gene is a member of a group of genes whose transcript levels are increased following stressful growth arrest conditions and treatment with DNA-damaging agents. The protein encoded by this gene responds to environmental stresses by mediating activation of the p38/JNK pathway via MTK1/MEKK4 kinase. The DNA damage-induced transcription of this gene is mediated by both p53-dependent and -independent mechanisms. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
Immunogen Purified recombinant human GADD45 α protein expressed in E.coli
Gene ID 1647
Swiss Prot P24522
Synonyms DDIT1; GADD45
Reactivity Transfected
Application WB
Recommended dilution WB: 1:500-1:1000
Calculated MW 18 kDa
Observed MW 22 kDa
Host species Mouse
Clonality Monoclonal
Clonality No. 6C3-G3-E9
Isotype IgG1
Purity Affinity Purification
Conjugation Un-conjugated
Storage/Stability Store at -20°C. Supplied in PBS, 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3. Stable for 12 months from date of receipt.

Western blot analysis of GADD45 alpha in CHO-K1 lysatesand CHO-K1 transfected by GADD45 alpha His fusion protein lysates using GADD45 alpha antibody.

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