Phospho-AMPK alpha 1 (Thr183)/AMPK alpha 2 (Thr172) Rabbit pAb - diagbio

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Phospho-AMPK alpha 1 (Thr183)/AMPK alpha 2 (Thr172) Rabbit pAb

db7369

Product Name : Phospho-AMPK alpha 1 (Thr183)/AMPK alpha 2 (Thr172) Rabbit pAb

Cat.No.: db7369

Synonyms : AMPK; AMPKa1

Application : WB

Reactivity : Human, Mouse, Rat

Host species : Rabbit

Background The protein encoded by this gene belongs to the ser/thr protein kinase family. It is the catalytic subunit of the 5'-prime-AMP-activated protein kinase (AMPK). AMPK is a cellular energy sensor conserved in all eukaryotic cells. The kinase activity of AMPK is activated by the stimuli that increase the cellular AMP/ATP ratio. AMPK regulates the activities of a number of key metabolic enzymes through phosphorylation. It protects cells from stresses that cause ATP depletion by switching off ATP-consuming biosynthetic pathways. Alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq, Jul 2008]
Immunogen A synthetic phosphopeptide corresponding to residues surrounding Thr183/Thr172 of human AMPK alpha 1/AMPK alpha 2
Gene ID 5562
Swiss Prot P54646
Synonyms AMPK; AMPKa1
Reactivity Human, Mouse, Rat
Application WB
Recommended dilution WB: 1:1000
Calculated MW 64,62 kDa
Observed MW 62 kDa
Host species Rabbit
Clonality Polyclonal
Isotype IgG
Purity Affinity Purification
Conjugation Un-conjugated
Storage/Stability Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

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