产品中心 Products Center
STAT3 Rabbit pAb

Product Name : STAT3 Rabbit pAb

Cat.No.: db7769

Synonyms : APRF; HIES; ADMIO; ADMIO1

Application : WB, IHC, ICC/IF, FC

Reactivity : Human, Mouse, Rat

Host species : Rabbit

  • Background The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is activated through phosphorylation in response to various cytokines and growth factors including IFNs, EGF, IL5, IL6, HGF, LIF and BMP2. This protein mediates the expression of a variety of genes in response to cell stimuli, and thus plays a key role in many cellular processes such as cell growth and apoptosis. The small GTPase Rac1 has been shown to bind and regulate the activity of this protein. PIAS3 protein is a specific inhibitor of this protein. Mutations in this gene are associated with infantile-onset multisystem autoimmune disease and hyper-immunoglobulin E syndrome. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Sep 2015]
  • Immunogen A synthetic peptide of human STAT3
  • Gene ID 6774
  • Swiss Prot P40763
  • Synonyms APRF; HIES; ADMIO; ADMIO1
  • Reactivity Human, Mouse, Rat
  • Application WB, IHC, ICC/IF, FC
  • Recommended dilution WB: 1:1000-1:5000
    IHC: 1:100
    ICC/IF: 1:100
    FC: 1:200
  • Calculated MW 88 kDa
  • Observed MW 88 kDa
  • Host species Rabbit
  • Clonality Polyclonal
  • Isotype IgG
  • Purity Affinity Purification
  • Conjugation Un-conjugated
  • Storage/Stability Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
订购信息
  • Package Price (RMB)
  • 20μL 598
  • 50μL 998
  • 100μL 1798
  • 货期:现货
For research use only. Not intended for diagnostic.