Phospho-ERK1 (pThr202/pTyr204) / ERK2 (pThr185/pTyr187) Rabbit pAb
Product Name :
Phospho-ERK1 (pThr202/pTyr204) / ERK2 (pThr185/pTyr187) Rabbit pAb
Cat.No.:
db8853
Synonyms :
ERK; p38; p40; p41; ERK2; ERT1; ERK-2; MAPK2; PRKM1; PRKM2; P42MAPK; p41mapk; p42-MAPK
Application :
WB, IP
Reactivity :
Human, Mouse, Rat
Host species :
Rabbit
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Background
This gene encodes a member of the MAP kinase family. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. The activation of this kinase requires its phosphorylation by upstream kinases. Upon activation, this kinase translocates to the nucleus of the stimulated cells, where it phosphorylates nuclear targets. One study also suggests that this protein acts as a transcriptional repressor independent of its kinase activity. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. Two alternatively spliced transcript variants encoding the same protein, but differing in the UTRs, have been reported for this gene. [provided by RefSeq, Jan 2014]
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Immunogen
A synthetic phosphopeptide corresponding to residues surrounding Thr202/Tyr204 of human Erk1
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Gene ID
5594
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Swiss Prot
P28482
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Synonyms
ERK; p38; p40; p41; ERK2; ERT1; ERK-2; MAPK2; PRKM1; PRKM2; P42MAPK; p41mapk; p42-MAPK
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Reactivity
Human, Mouse, Rat
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Application
WB, IP
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Recommended dilution
WB: 1:2000
IP: 1:20
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Calculated MW
41 kDa
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Observed MW
44,42 kDa
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Host species
Rabbit
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Clonality
Polyclonal
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Isotype
IgG
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Purity
Affinity Purification
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Conjugation
Un-conjugated
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Storage/Stability
Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
订购信息
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Package
Price (RMB)
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20μL
698
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50μL
1398
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100μL
2398
- 货期：现货
For research use only. Not intended for diagnostic.
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