VEGF Receptor 1 Rabbit pAb - diagbio | 戴格生物

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VEGF Receptor 1 Rabbit pAb

db9395

Product Name : VEGF Receptor 1 Rabbit pAb

Cat.No.: db9395

Synonyms : FLT; FLT-1; VEGFR1; VEGFR-1

Application : WB, IHC, IP

Reactivity : Human, Mouse, Rat

Host species : Rabbit

Background This gene encodes a member of the vascular endothelial growth factor receptor (VEGFR) family. VEGFR family members are receptor tyrosine kinases (RTKs) which contain an extracellular ligand-binding region with seven immunoglobulin (Ig)-like domains, a transmembrane segment, and a tyrosine kinase (TK) domain within the cytoplasmic domain. This protein binds to VEGFR-A, VEGFR-B and placental growth factor and plays an important role in angiogenesis and vasculogenesis. Expression of this receptor is found in vascular endothelial cells, placental trophoblast cells and peripheral blood monocytes. Multiple transcript variants encoding different isoforms have been found for this gene. Isoforms include a full-length transmembrane receptor isoform and shortened, soluble isoforms. The soluble isoforms are associated with the onset of pre-eclampsia.[provided by RefSeq, May 2009]
Immunogen A synthetic peptide of human VEGF Receptor 1
Gene ID 2321
Swiss Prot P17948
Synonyms FLT; FLT-1; VEGFR1; VEGFR-1
Reactivity Human, Mouse, Rat
Application WB, IHC, IP
Recommended dilution WB: 1:1000
IHC: 1:50
IP: 1:20
Calculated MW 151 kDa
Observed MW 180 kDa
Host species Rabbit
Clonality Polyclonal
Isotype IgG
Purity Affinity Purification
Conjugation Un-conjugated
Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

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