Human IL10 ELISA Kit - diagbio | 戴格生物

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Human IL10 ELISA Kit

EKT10110

Datasheet

Product Name : Human IL10 ELISA Kit

Cat.No.: EKT10110

Synonyms : CSIF; TGIF; GVHDS; IL-10; IL10A

Application : ELISA

Reactivity : Human

Background The protein encoded by this gene is a cytokine produced primarily by monocytes and to a lesser extent by lymphocytes. This cytokine has pleiotropic effects in immunoregulation and inflammation. It down-regulates the expression of Th1 cytokines, MHC class II Ags, and costimulatory molecules on macrophages. It also enhances B cell survival, proliferation, and antibody production. This cytokine can block NF-kappa B activity, and is involved in the regulation of the JAK-STAT signaling pathway. Knockout studies in mice suggested the function of this cytokine as an essential immunoregulator in the intestinal tract. Mutations in this gene are associated with an increased susceptibility to HIV-1 infection and rheumatoid arthritis.
Gene ID 3586
Swiss Prot P22301
Synonyms CSIF; TGIF; GVHDS; IL-10; IL10A
Reactivity Human
Application ELISA
Sensitivity 6.73 pg/mL
Detection Method Sandwich-ELISA
Detection Range 46.88 pg/mL-3000 pg/mL
Sample type Cell culture supernatant, Serum, Plasma,Tissue extracts
Storage/Stability Reference standard and 100X HRP-streptavidin concentrate are stored at -20°C, others put in 4°C. Stable for 12 months from date of receipt.

Example of Human IL10standard curve. Background-subtracted data values (mean +/- SD) are graphed.

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