Human TNF-α ELISA Kit - diagbio | 戴格生物

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Human TNF-α ELISA Kit

EKT10113

Datasheet

Product Name : Human TNF-α ELISA Kit

Cat.No.: EKT10113

Synonyms : DIF; TNFA; IMD127; TNFSF2; TNLG1F; TNF-alpha

Application：

Reactivity : Human

Background This gene encodes a multifunctional proinflammatory cytokine that belongs to the tumor necrosis factor (TNF) superfamily. This cytokine is mainly secreted by macrophages. It can bind to, and thus functions through its receptors TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. This cytokine is involved in the regulation of a wide spectrum of biological processes including cell proliferation, differentiation, apoptosis, lipid metabolism, and coagulation. This cytokine has been implicated in a variety of diseases, including autoimmune diseases, insulin resistance, psoriasis, rheumatoid arthritis ankylosing spondylitis, tuberculosis, autosomal dominant polycystic kidney disease, and cancer. Mutations in this gene affect susceptibility to cerebral malaria, septic shock, and Alzheimer disease. Knockout studies in mice also suggested the neuroprotective function of this cytokine.
Gene ID 7124
Swiss Prot P01375
Synonyms DIF; TNFA; IMD127; TNFSF2; TNLG1F; TNF-alpha
Reactivity Human
Application ELISA
Sensitivity 6.82 pg/mL
Detection Method Sandwich-ELISA
Detection Range 15.63 pg/mL-1000 pg/mL
Sample type Cell culture supernatant, Serum, Plasma,Tissue extracts
Storage/Stability Reference standard and 100X HRP-streptavidin concentrate are stored at -20°C, others put in 4°C. Stable for 12 months from date of receipt.

Example of Human TNF-α standard curve. Background-subtracted data values (mean +/- SD) are graphed.

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