Human IL1β ELISA Kit - diagbio | 戴格生物

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Human IL1β ELISA Kit

EKT10118

Datasheet

Product Name : Human IL1β ELISA Kit

Cat.No.: EKT10118

Synonyms : IL-1; IL1F2; IL1beta; IL1-BETA

Application：

ELISA

Reactivity : Human

Background The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine is produced by activated macrophages as a proprotein, which is proteolytically processed to its active form by caspase 1 (CASP1/ICE). This cytokine is an important mediator of the inflammatory response, and is involved in a variety of cellular activities, including cell proliferation, differentiation, and apoptosis. The induction of cyclooxygenase-2 (PTGS2/COX2) by this cytokine in the central nervous system (CNS) is found to contribute to inflammatory pain hypersensitivity. Similarly, IL-1B has been implicated in human osteoarthritis pathogenesis. Patients with severe Coronavirus Disease 2019 (COVID-19) present elevated levels of pro-inflammatory cytokines such as IL-1B in bronchial alveolar lavage fluid samples. The lung damage induced by the Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is to a large extent, a result of the inflammatory response promoted by cytokines such as IL-1B. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2.
Gene ID 3553
Swiss Prot P01584
Synonyms IL-1; IL1F2; IL1beta; IL1-BETA
Reactivity Human
Application ELISA
Sensitivity 5.11 pg/mL
Detection Method Sandwich-ELISA
Detection Range 14.06 pg/mL-900 pg/mL
Sample type Cell culture supernatant, Serum, Plasma,Tissue extracts
Storage/Stability Reference standard and 100X HRP-streptavidin concentrate are stored at -20°C, others put in 4°C. Stable for 12 months from date of receipt.

Example of Human IL1β standard curve. Background-subtracted data values (mean +/- SD) are graphed.

订购信息

Package Price (RMB)
48T 1518
96T 2580
货期：一周内