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Product Name : Mouse VEGFA ELISA Kit
Cat.No.: EKT10132
Synonyms : Vpf; Vegf; L-VEGF
Application：
Reactivity : Mouse
- Background This gene is a member of the PDGF/VEGF growth factor family. It encodes a heparin-binding protein, which exists as a disulfide-linked homodimer. This growth factor induces proliferation and migration of vascular endothelial cells, and is essential for both physiological and pathological angiogenesis. Disruption of this gene in mice resulted in abnormal embryonic blood vessel formation. This gene is upregulated in many known tumors and its expression is correlated with tumor stage and progression. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. There is also evidence for alternative translation initiation from upstream non-AUG (CUG) codons resulting in additional isoforms. A recent study showed that a C-terminally extended isoform is produced by use of an alternative in-frame translation termination codon via a stop codon readthrough mechanism, and that this isoform is antiangiogenic. Expression of some isoforms derived from the AUG start codon is regulated by a small upstream open reading frame, which is located within an internal ribosome entry site.
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Gene ID
22339
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Swiss Prot
Q00731
- Synonyms Vpf; Vegf; L-VEGF
- Reactivity Mouse
- Application ELISA
- Sensitivity 4.17 pg/mL
- Detection Method Sandwich-ELISA
- Detection Range 7.81 pg/mL-500 pg/mL
- Sample type Cell culture supernatant, Serum, Plasma,Tissue extracts
- Storage/Stability Reference standard and 100X HRP-streptavidin concentrate are stored at -20°C, others put in 4°C. Stable for 12 months from date of receipt.
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Example of Mouse VEGFA standard curve. Background-subtracted data values (mean +/- SD) are graphed.
订购信息
- Package Price (RMB)
- 48T 1518
- 96T 2580
- 货期：一周内
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For research use only. Not intended for diagnostic.
