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Human IL17A ELISA Kit
EKT10140
Datasheet

Product Name : Human IL17A ELISA Kit

Cat.No.: EKT10140

Synonyms : IL17; CTLA8; IL-17; ILA17; CTLA-8; IL-17A

Application：

Reactivity : Human

  • Background This gene is a member of the IL-17 receptor family which includes five members (IL-17RA-E) and the encoded protein is a proinflammatory cytokine produced by activated T cells. IL-17A-mediated downstream pathways induce the production of inflammatory molecules, chemokines, antimicrobial peptides, and remodeling proteins. The encoded protein elicits crucial impacts on host defense, cell trafficking, immune modulation, and tissue repair, with a key role in the induction of innate immune defenses. This cytokine stimulates non-hematopoietic cells and promotes chemokine production thereby attracting myeloid cells to inflammatory sites. This cytokine also regulates the activities of NF-kappaB and mitogen-activated protein kinases and can stimulate the expression of IL6 and cyclooxygenase-2 (PTGS2/COX-2), as well as enhance the production of nitric oxide (NO). IL-17A plays a pivotal role in various infectious diseases, inflammatory and autoimmune disorders, and cancer. High levels of this cytokine are associated with several chronic inflammatory diseases including rheumatoid arthritis, psoriasis and multiple sclerosis. The lung damage induced by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is to a large extent, a result of the inflammatory response promoted by cytokines such as IL17A.
  • Gene ID 3605
  • Swiss Prot Q16552
  • Synonyms IL17; CTLA8; IL-17; ILA17; CTLA-8; IL-17A
  • Reactivity Human
  • Application ELISA
  • Sensitivity 0.25 pg/mL
  • Detection Method Sandwich-ELISA
  • Detection Range 1.56 pg/mL-100 pg/mL
  • Sample type Cell culture supernatant, Serum, Plasma,Tissue extracts
  • Storage/Stability Reference standard and 100X HRP-streptavidin concentrate are stored at -20°C, others put in 4°C. Stable for 12 months from date of receipt.
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  • Example of Human IL17A standard curve. Background-subtracted data values (mean +/- SD) are graphed.
订购信息
  • Package Price (RMB)
  • 48T 1518
  • 96T 2580
  • 货期：一周内
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For research use only. Not intended for diagnostic.