Human CCL5 ELISA Kit - diagbio | 戴格生物

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Human CCL5 ELISA Kit

EKT10147

Datasheet

Product Name : Human CCL5 ELISA Kit

Cat.No.: EKT10147

Synonyms : SISd; eoCP; SCYA5; RANTES; TCP228; D17S136E; SIS-delta

Application：

Reactivity : Human

Background This gene is one of several chemokine genes clustered on the q-arm of chromosome 17. Chemokines form a superfamily of secreted proteins involved in immunoregulatory and inflammatory processes. The superfamily is divided into four subfamilies based on the arrangement of the N-terminal cysteine residues of the mature peptide. This chemokine, a member of the CC subfamily, functions as a chemoattractant for blood monocytes, memory T helper cells and eosinophils. It causes the release of histamine from basophils and activates eosinophils. This cytokine is one of the major HIV-suppressive factors produced by CD8+ cells. It functions as one of the natural ligands for the chemokine receptor chemokine (C-C motif) receptor 5 (CCR5), and it suppresses in vitro replication of the R5 strains of HIV-1, which use CCR5 as a coreceptor. Alternative splicing results in multiple transcript variants that encode different isoforms.
Gene ID 6352
Swiss Prot P13501
Synonyms SISd; eoCP; SCYA5; RANTES; TCP228; D17S136E; SIS-delta
Reactivity Human
Application ELISA
Sensitivity 0.94 pg/mL
Detection Method Sandwich-ELISA
Detection Range 3.13 pg/mL-200 pg/mL
Sample type Cell culture supernatant, Serum, Plasma,Tissue extracts
Storage/Stability Reference standard and 100X HRP-streptavidin concentrate are stored at -20°C, others put in 4°C. Stable for 12 months from date of receipt.

Example of Human RANTES standard curve. Background-subtracted data values (mean +/- SD) are graphed.

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