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Human IDH1 ELISA Kit
EKT10150
Datasheet

Product Name : Human IDH1 ELISA Kit

Cat.No.: EKT10150

Synonyms : IDH; IDP; IDCD; IDPC; PICD; HEL-216; HEL-S-26

Application：

Reactivity : Human

  • Background Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which utilizes NAD(+) as the electron acceptor and the other NADP(+). Five isocitrate dehydrogenases have been reported: three NAD(+)-dependent isocitrate dehydrogenases, which localize to the mitochondrial matrix, and two NADP(+)-dependent isocitrate dehydrogenases, one of which is mitochondrial and the other predominantly cytosolic. Each NADP(+)-dependent isozyme is a homodimer. The protein encoded by this gene is the NADP(+)-dependent isocitrate dehydrogenase found in the cytoplasm and peroxisomes. It contains the PTS-1 peroxisomal targeting signal sequence. The presence of this enzyme in peroxisomes suggests roles in the regeneration of NADPH for intraperoxisomal reductions, such as the conversion of 2, 4-dienoyl-CoAs to 3-enoyl-CoAs, as well as in peroxisomal reactions that consume 2-oxoglutarate, namely the alpha-hydroxylation of phytanic acid. The cytoplasmic enzyme serves a significant role in cytoplasmic NADPH production. Alternatively spliced transcript variants encoding the same protein have been found for this gene.
  • Gene ID 3417
  • Swiss Prot O75874
  • Synonyms IDH; IDP; IDCD; IDPC; PICD; HEL-216; HEL-S-26
  • Reactivity Human
  • Application sELISA
  • Sensitivity 211.23 pg/mL
  • Detection Method Sandwich-ELISA
  • Detection Range 781.25 pg/mL-50000 pg/mL
  • Sample type Cell culture supernatant, Serum, Plasma,Tissue extracts
  • Storage/Stability Reference standard and 100X HRP-streptavidin concentrate are stored at -20°C, others put in 4°C. Stable for 12 months from date of receipt.
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  • Example of Human IDH1 standard curve. Background-subtracted data values (mean +/- SD) are graphed.
订购信息
  • Package Price (RMB)
  • 48T 1518
  • 96T 2580
  • 货期：一周内
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For research use only. Not intended for diagnostic.