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Anterior Gradient 2 (DGR12035) Rabbit mAb
db11005
Datasheet
- Background This gene encodes a member of the disulfide isomerase (PDI) family of endoplasmic reticulum (ER) proteins that catalyze protein folding and thiol-disulfide interchange reactions. The encoded protein has an N-terminal ER-signal sequence, a catalytically active thioredoxin domain, and a C-terminal ER-retention sequence. This protein plays a role in cell migration, cellular transformation and metastasis and is as a p53 inhibitor. As an ER-localized molecular chaperone, it plays a role in the folding, trafficking, and assembly of cysteine-rich transmembrane receptors and the cysteine-rich intestinal gylcoprotein mucin. This gene has been implicated in inflammatory bowel disease and cancer progression. [provided by RefSeq, Mar 2017]
- Immunogen A synthetic peptide of human Anterior Gradient 2
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Gene ID
10551
-
Swiss Prot
O95994
- Synonyms AG2; AG-2; HPC8; GOB-4; HAG-2; XAG-2; PDIA17; HEL-S-116
- Reactivity Human
- Application WB, IHC-P, ICC/IF, FC, IP
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Recommended dilution
WB: 1:1000-1:5000
IHC-P: 1:200-1:500
ICC/IF: 1:100
FC: 1:20-1:50
IP: 1:20 - Calculated MW 20 kDa
- Observed MW 18 kDa
- Host species Rabbit
- Clonality Monoclonal
- Clonality No. DGR12035
- Isotype IgG
- Purity Affinity Purification
- Conjugation Un-conjugated
- Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
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Western blot detection of Anterior Gradient 2 in K562,C6 cell lysates using Anterior Gradient 2 antibody(1:1000 diluted). -
Immunohistochemical analysis of paraffin-embedded colon using db11005 antibody. -
Immunofluorescent analysis of MCF-7 cells using db11005 antibody (green), and DAPI (blue).
订购信息
- Package Price (RMB)
- 10μL 398
- 20μL 698
- 50μL 1398
- 100μL 2398
- 货期：现货
相关产品
For research use only. Not intended for diagnostic.
