您当前的位置：
PABPN1 (DGR12294) Rabbit mAb
db11024
Datasheet
- Background This gene encodes an abundant nuclear protein that binds with high affinity to nascent poly(A) tails. The protein is required for progressive and efficient polymerization of poly(A) tails at the 3' ends of eukaryotic transcripts and controls the size of the poly(A) tail to about 250 nt. At steady-state, this protein is localized in the nucleus whereas a different poly(A) binding protein is localized in the cytoplasm. This gene contains a GCG trinucleotide repeat at the 5' end of the coding region, and expansion of this repeat from the normal 6 copies to 8-13 copies leads to autosomal dominant oculopharyngeal muscular dystrophy (OPMD) disease. Related pseudogenes have been identified on chromosomes 19 and X. Read-through transcription also exists between this gene and the neighboring upstream BCL2-like 2 (BCL2L2) gene. [provided by RefSeq, Dec 2010]
- Immunogen A synthetic peptide of human PABPN1
-
Gene ID
8106
-
Swiss Prot
Q86U42
- Synonyms OPMD; PAB2; PABII; PABP2; PABP-2
- Reactivity Human,Mouse,Rat
- Application WB, IHC-P, ICC/IF, FC, IP
-
Recommended dilution
WB: 1:1000-1:5000
IHC-P: 1:200-1:1000
ICC/IF: 1:100-1:200
FC: 1:20-1:50
IP: 1:20-1:50 - Calculated MW 33 kDa
- Observed MW 50 kDa
- Host species Rabbit
- Clonality Monoclonal
- Clonality No. DGR12294
- Isotype IgG
- Purity Affinity Purification
- Conjugation Un-conjugated
- Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
-
Western blot detection of PABPN1 in Jurkat,Hela,COS7,Raji cell lysates using PABPN1 antibody(1:1000 diluted). -
Immunohistochemical analysis of paraffin-embedded human breast cancer using db11024 antibody.
订购信息
- Package Price (RMB)
- 10μL 398
- 20μL 698
- 50μL 1398
- 100μL 2398
- 货期：现货
相关产品
For research use only. Not intended for diagnostic.
