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SFT (DGR32561) Rabbit mAb
db11149
Datasheet
- Background The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is closely related to a stimulator of iron transport (SFT), and is up-regulated in hereditary hemochromatosis. It also functions in the ubiquitination of the tumor-suppressor protein p53 and the hypoxia-inducible transcription factor HIF1alpha by interacting with the E1 ubiquitin-activating enzyme and the E3 ubiquitin-protein ligases. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2011]
- Immunogen A synthetic peptide of human SFT
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Gene ID
7321
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Swiss Prot
P51668
- Synonyms SFT; UBCH5; UBC4/5; UBCH5A; E2(17)KB1
- Reactivity Human,Mouse,Rat
- Application WB, IHC-P, FC, IP
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Recommended dilution
WB: 1:2000-1:20000
IHC-P: 1:50-1:100
FC: 1:10-1:100
IP: 1:10-1:100 - Calculated MW 17 kDa
- Observed MW 17 kDa
- Host species Rabbit
- Clonality Monoclonal
- Clonality No. DGR32561
- Isotype IgG
- Purity Affinity Purification
- Conjugation Un-conjugated
- Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
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Western blot detection of SFT in Hela,HL-60 using SFT antibody(1:1000 diluted) -
Immunohistochemical analysis of paraffin-embedded human lung cancer using db11149 antibody.
订购信息
- Package Price (RMB)
- 10μL 398
- 20μL 698
- 50μL 1398
- 100μL 2398
- 货期：现货
相关产品
For research use only. Not intended for diagnostic.
